Cardiorenal Syndrome: An Overview
نویسندگان
چکیده
Cardiorenal syndrome (CRS) is a complex spiral of vascular disease entity, in which affliction of one organ (kidney) may adversely impact the functioning of the other (heart). Recent consensus conference has clearly defined its various types and pathophysiology. Improved survival, cardiovascular risk factors (diabetes, hypertension, dyslipidemia), diagnostic and therapeutic intervention [contrast agent, improper diuretic usage, nonsteroidal anti-inflammatory drugs (NSAIDs)] are some contributors in its causation. A proper understanding of its mechanism and subsequent individualized approach can stall its progressive spiral. This chapter addresses preventive and established therapeutic strategies such as diuretics and inotropes, in the CRS as well as novel therapies that hold promise, such as arginine vasopressin antagonists, adenosine A1 receptor antagonists and ultrafiltration.
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